The marquee game of the week is No. 2 Oregon hosting No. 7 Indiana in a Big Ten contest.
In the SEC, No. 8 Alabama will face No. 14 Missouri, while No. 6 Oklahoma plays No. 19 Texas.
Other key games include No. 1 Ohio State at No. 17 Illinois and No. 15 Michigan at Southern California.
The college football season hits the halfway point in Week 7, with conference play in full swing. There are four Top 25 matchups for our panel of pickers to consider, but there is always the possibility of an upset or two.
The Big Ten features the week’s marquee contest as No. 2 Oregon hosts No. 7 Indiana. Elsewhere in the league, top-ranked Ohio State hits the road at No. 17 Illinois, No. 15 Michigan heads west to take on Southern California, and No. 22 Penn State looks to get right against Northwestern.
As usual, there’s plenty of ranked-on-ranked action in SEC country as well. No. 8 Alabama takes on yet another unbeaten opponent at No. 14 Missouri, and No. 6 Oklahoma and No. 19 Texas square off in their annual Red River showdown in Dallas.
Here’s how our staffers think those games will unfold, and where they think other Top 25 surprises might happen.
